At which phase do cells specifically ensure that the chromosomes are accurately separated into daughter cells?

During the anaphase of cell division, the chromosomes are specifically pulled apart and moved toward opposite poles of the cell. This phase follows metaphase, where chromosomes align at the equatorial plate, and it is crucial for ensuring that each daughter cell receives an identical set of chromosomes. In anaphase, the cohesion proteins that hold sister chromatids together are cleaved, allowing the chromatids to be separated and drawn toward the centrioles that are at opposite ends of the dividing cell.

The accuracy of this separation is vital for maintaining the correct number of chromosomes in the resulting daughter cells, thus preventing aneuploidy, which is a condition characterized by an abnormal number of chromosomes. Proper mechanics during anaphase are monitored by various checkpoint mechanisms within the cell to ensure fidelity in chromosome segregation.